Safety
Memodyne Side Effects: What Each Ingredient May Cause
Strong reactions to one Memodyne capsule are unlikely, and mild stomach trouble is the main effect seen in studies.
L-arginine can pull blood pressure or blood sugar too low alongside certain drugs, and people who just had a heart attack should skip it (Mayo Clinic, L-arginine).
Written by the Memodyne editorial teamUpdated
Short version
What side effects can Memodyne cause?
Mild stomach trouble is the most likely one, and research saw even that at doses many times larger than a capsule.
Nobody has tested the Memodyne formula itself. Each ingredient has been studied, though, usually in grams.
| Label line | Per capsule | Effects reported in research | One capsule vs research |
|---|---|---|---|
| L-arginine, base and AKG | 200 mg + 200 mg | Nausea, belly pain, diarrhea, bloating; gout, allergy, worse asthma in some people (Mayo Clinic, L-arginine). In athletes, 9-30 g daily brought gut trouble and slightly lower readings (NIH ODS, Exercise supplements) | Roughly 1/5 of the smallest arginine dose tested |
| L-citrulline, HCl and malate | 100 mg + 100 mg | Stomach discomfort in 6 of 41 weightlifters given 8 g of citrulline malate (NIH ODS, Exercise supplements) | About 1/15 of the smallest citrulline dose tested |
| Beta-alanine | 40 mg | Harmless pins-and-needles on the face, neck, hands or upper body for 60-90 minutes after 800 mg or more at once; itchy skin (NIH ODS, Exercise supplements) | About 1/40 of the smallest dose tested |
| Niacin | 7.5 mg NE | Red, warm skin once nicotinic acid reaches 30-50 mg and up (NIH ODS, Niacin) | Well under that range; the panel never names the niacin type |
| Calcium carbonate | 18 mg | No concern listed by our sources | 1.5% of the Daily Value |
By ingredient
Which Memodyne ingredient is most likely to cause a problem?
L-arginine, because its pull on blood vessels can stack with heart and diabetes medicines.
L-arginine
Mayo Clinic tells people fresh from a heart attack to avoid it; deaths may be more likely in that group (Mayo Clinic, L-arginine).
L-citrulline
Nonathletes took up to 6 g a day for four weeks without trouble. Long-term safety is still an open question (NIH ODS, Exercise supplements).
Beta-alanine
The pre-workout tingle needs roughly 800 mg in one go. A capsule carries 40 mg (NIH ODS, Exercise supplements).
Niacin
The adult ceiling from pills and fortified foods is 35 mg daily (NIH ODS, Niacin). Add 7.5 mg NE to your multivitamin's niacin.
On the bottle
What does the Memodyne label warn about?
Dose limits, pregnancy, age under 18 and known health conditions. It names no specific drug.
The printed caution reads: CAUTION: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children. Do not use if safety seal is damaged or missing.
Blood pressure pills, nitrates and blood thinners go unmentioned, even with L-arginine on the panel. The whole wrap is typed out on the Supplement Facts page.
Medicines
Which medicines interact with Memodyne?
Mayo Clinic flags seven medicine groups for L-arginine. NIH adds two tuberculosis drugs for niacin.
| Medicine group | What it treats | Possible effect with Memodyne | Source |
|---|---|---|---|
| Blood pressure drugs | High blood pressure | Readings sink lower than your doctor intended | (Mayo Clinic, L-arginine) |
| Nitrates | Chest pain (angina) | Pressure could crash | (Mayo Clinic, L-arginine) |
| Sildenafil | Erectile dysfunction | Pressure could crash | (Mayo Clinic, L-arginine) |
| Isoproterenol | Heart rhythm, given in hospital | Pressure could crash | (Mayo Clinic, L-arginine) |
| Anticoagulants, antiplatelets | Clot prevention | Easier bruising and bleeding | (Mayo Clinic, L-arginine) |
| Diabetes drugs | High blood sugar | Glucose dips under a safe level | (Mayo Clinic, L-arginine) |
| Potassium-sparing diuretics | Fluid, blood pressure | Potassium builds up in the blood | (Mayo Clinic, L-arginine) |
| Isoniazid, pyrazinamide | Tuberculosis | They interfere with niacin | (NIH ODS, Niacin) |
A pharmacist can run every medicine you use against the seven label lines in minutes. Show them the actual bottle so nothing gets guessed.
Search mix-up
Why do Memodyne side effect searches show memantine?
The two names look alike, so search engines fill the results with research on a prescription drug.
Namenda is the brand name of memantine, a prescription drug for Alzheimer's disease. Type "Memodyne side effects" and the results often list memantine trials and case reports. Those reactions belong to that drug, its doses and its patients, not to a capsule of amino acids and niacin.
Memodyne contains no memantine and cannot stand in for it. Anyone on memantine who adds the supplement brings in the L-arginine questions above. Never stop or change a dose on your own.
Our post on lookalike names sorts out Melodyne too.
Ready to try Memodyne?6 bottles $294 ($49 each) · 60-day refund window · free U.S. shipping on 3 or 6
Order nowKnow the signs
How can you tell if your pressure or sugar has dropped?
Both often start with dizziness or weakness. These are general signs, not a test for Memodyne.
Pressure running low
- A woozy, lightheaded feeling on rising from a chair or bed
- Near-fainting or blacking out
- Blurred eyesight
- Queasiness
- Unusual tiredness
Sugar running low
- Shaky hands
- Sweating, clammy skin
- A racing heartbeat
- Sudden hunger or crankiness
- Muddled thinking
On pressure or diabetes medicine? Check your readings and call your doctor if these appear.
Stop and ask
When should you stop Memodyne?
Put the bottle aside and call your doctor if any of these happen.
- Hives, a rash, swollen lips or face, or wheezing
- Asthma flaring after you start
- Diarrhea, cramps or bloating that lasts beyond a few days
- Dizzy spells, or home readings trending down
- A sudden hot, painful, swollen joint, which can be gout
- New or heavier bruising or bleeding
- A positive pregnancy test
Dropping the supplement is up to you; a prescription is your doctor's call. Refund steps are in the guarantee terms.
Emergency
Which symptoms need 911, not a supplement check?
Sudden numbness or weakness, often on one side of the body. Sudden confusion or slurred, garbled speech. Sudden trouble seeing or walking. A sudden, severe headache. These can mean a stroke (CDC, Stroke signs), and every minute counts.
Reporting
Where can you file a report about a Memodyne reaction?
With your doctor first, then with the FDA, so the event is on record.
Get checked
Anything beyond mild stomach upset deserves a doctor or urgent care visit. Take the bottle with you.
Write it down
Lot number, start date, symptoms, and every other product you took that week.
Tell FDA MedWatch
The FDA takes supplement reaction reports from the public through its MedWatch online form or at 1-800-FDA-1088. Doctors can send one too.
Let the order desk at +1 (302) 200-3480 know too.
FAQ
Memodyne side effect questions
Does Memodyne have side effects?
It can, though no study measured them for the formula. Its ingredients caused gut upset and lower blood pressure, mostly at gram doses (NIH ODS, Exercise supplements) (Mayo Clinic, L-arginine). A capsule holds milligrams, so mild effects or none are most likely.
Can Memodyne cause diarrhea or an upset stomach?
Possibly, though it is unlikely at one capsule. Mayo Clinic lists nausea, belly pain, diarrhea and bloating for L-arginine (Mayo Clinic, L-arginine), and citrulline bothered some weightlifters at 8 g (NIH ODS, Exercise supplements). If loose stools last several days, set the capsule aside and call your doctor.
Is Memodyne safe with a blood thinner like warfarin?
Ask your prescriber before combining them. Mayo Clinic says L-arginine with anticoagulant or antiplatelet drugs may raise bleeding risk (Mayo Clinic, L-arginine). The Memodyne label is silent on this, so let the doctor decide.
Can I take Memodyne with Viagra or nitroglycerin?
Only with a doctor's OK. Per Mayo Clinic, L-arginine plus sildenafil, or plus nitrates for chest pain, can send blood pressure too low (Mayo Clinic, L-arginine).
Does the niacin in Memodyne cause flushing?
Flushing is unlikely. Warm, red skin from niacin starts around 30-50 mg of nicotinic acid, and a capsule lists 7.5 mg NE (NIH ODS, Niacin). The niacin type is not named, so count it with any B-complex or multivitamin you already use.
Are Memodyne side effects the same as memantine side effects?
No. Memantine (Namenda) is a dementia prescription, and its side-effect data come from trials of that medicine. Memodyne is a supplement of amino acids, niacin and calcium.
Can Memodyne lower blood sugar?
It could add to diabetes medicine. Mayo Clinic says L-arginine taken with glucose-lowering drugs could drag glucose too low (Mayo Clinic, L-arginine). If you use insulin or diabetes tablets, check with your doctor first and test more often during the first weeks.
Who wrote this
Written and reviewed by
Plain-language pages built from the label, the sales page and linked public health sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by a USA authorized retailer that sells Memodyne, not by the maker (the label says distributed by Gex Corporation LLP, Ogden, UT). We earn money when you buy through our order links.
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Every line of the Memodyne bottle, typed out and explained, plus what the label leaves out and how to match your own bottle.
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